Born in Odessa, Russia, in 1883, he became primarily a portrait painter and studied at the Art Students League of the City of New York. Mirsky produced miniature portraits as well as life-size portraits. He died in New York in 1980.
His New York household included his daughters Eda Mann and Kitty Brandfield, both also painters. He has three granddaughters, including Erica Jong, the famous writer.
